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Some people believe that natural substances,must be safe,because they're natural,but this is not always true. Arsenic and nightshade are two substances that people have used for disease treatment,but both can be deadly.
 
Non-traditional treatments are often,some  form of complementary or alternate medicine. In the majority of cases, researchers have not studied these treatments using randomized-double-blind trials or time-tested with large participants,and using acceptable scientific methods.
 
Many so-called "trials" are done to all healthy individuals,on a short-selective-few,and employing haphazard methods for "trial" purposes. Many can be classified as promotions.
 
Many people with RA become discouraged with typical treatments because the disease progresses over time,and often worsens. Consequently they search for Alternate Therapy. But RA patients need to be careful because treatment not shown to be safe and effective through scientific studies may be dangerous.
 
The benefits of treatment in controlling RA,should be greater then the risk of unwanted, harmful side effects. Since arthritic symptoms may come and go,a person using an unproven remedy may mistakenly think the remedy positive, simply because he or she tried it when symptoms were going into a natural remission state.
 
A 1/11/01 issue of J.A.M.A.--This presentation can help to minimize potential negative effects or interaction with drugs used in the hospital, says the authors, who are anesthesiologists at a University of Chicago.
 
Epherda can present a risk of irregular heart rhythms.
 
Ginko, can increase bleeding .
 
St.John's Wort can interfere with the effect of drugs,according to the authors-St. John's Wort went through a lengthy extensive study through the NIH and the many claims of it can be compared to placebo. The study is availabe at the NIH website to those who are interested.
 
Surveys show that up to one third of patients admitted to hospitals for surgery have been taking some sort of herbal products. Most of the time,they tell their doctors,some don't ask. MD's generally ask their patients what other medicines they are taking.
 
But patients often may not mention herbs because they don't consider them medicines,or they believe their MD's are prejudicial against their product,according to the study.
 
A pharmacist and drug therapy director-manager at a major U.S. metropolitan hospital said problems have occurred when physicians have not been aware of herbal products that have been taken.
 
He cited some cases of unexpected bleeding during a cardiac catheterization,a procedure in which a slender tube is inserted into a large blood vessel to evaluate heart function. "We've had problems with ginko especially, as a contributing factor in bleeding.
 
The JAMA study listed these concerns ,among others for most popular herbal preparations sold in the U.S.,echinacea,can stimulate the immune system during-short-term use but suppresses immune system if used longer than 8 weeks.
 
Ephedra-Increases blood pressure and heart rates-can lead to heart attack or stroke. Use with other drugs can produce abnormal heart rhythm. Once used for treating colds. Recent research suggests it is useless in treating cold symptoms.
 
Garlic,ginko.and ginseng-can increase bleeding.
 
Kava and Valeria-can increase  the effect of sedatives.
 
St. Johns Wort-can interfere with effects of other drugs.
 
Surgery and other procedures always put the body under some degree of stress and present  the possibility of complications, including bleeding,blood-pressure and heart rhythm changes.infections and allergic reactions.
 
Bleeding is a particular delicate area of concern for many procedures, a expert comments : 'You want to control every factor you can control to prevent clotting,but not so much you get bleeding".  Certain herbal products represent a "unknown variable"  that could upset balance,the expert continued. "The one that really scares me is ephedra for a whole variety of reasons,he added. :It's a drug , period."  In combination with other drug,it produces arrhythmis,that can be a problem for an anesthesiologist during surgery because it may make some of the drugs used to maintain blood pressure less effective or ineffective".
 
Echinacea,recommended as a immune system stimulant,may be just what someone on immunosuppressive treatment for rheumatoid arthritis or systemic lupus doesn't need.  Echinacea has been touted to be able to boost the body's ability to fight off infection. It may cause liver toxicity. Patients using methotrexate or Arava should avoid  it.
 
Garlic has been used to lower blood pressure and cholestral.  Allergic reactions include skin inflammation and stomach upset. Studies in rats have shown decrease in male rats ability to make sperm cells. Garlic may decrease normal blood clotting. 
 
Feverfew used mostly for migrane headaches can cause allergic reactions,especially in persons who are allergic to chamomile, ragweed, or yarrow.  NSAIDs can reduce the effect of feverfew. A condition called  "post feverfew syndrome" features symptoms including headache, nervousness, insomia, stiffness,joint pain,tiredness,and nervousness.  Feverfew can affect normal blood clotting. Despite a lack of evidence that feverfew can relieve arthritis pain, many  patients in the U.K. use it. The only clinical trial (so far ) on feverfew showed negative results.
 
Ginger used mostly for nausea and bowel spasms may lead to blood thinning do not use with anticoagulants such as warfarin (coumadin).
To gain full benefit in blocking the inflammatory cascade,it is wise to avoid it in large quantities (more than 1-2 grams a day during the first trimester during pregnancy. A standard dose of ginger is 500 mg to 7 grams of powdered root or up to 50 grams of fresh,lightly cooked root. It is relatively safe to use as a antioxidant.
 
 Chamomile is often used in the form of tea as a sedative. Allergic reactions can occur particularily in persons  allergic to ragweed. Abdominal cramps, tightness in throat, swelling of the lips,throat and eyes,itching all over the body.  It may decrease normal blood clotting.
 
Celery seed and celery seed oil have recent but fairly strong history of folk use in Europe as a antirheumatic agent and is used commonly in Australia.  Celery seed is also listed as a traditional antirheumatic herb by the British Herbal Pharmacopoeia and Germany's Commission E,although both respected bodies declare a lack of clinical evidence.
Be aware that celery seed is contraindicated in kidney disorders and celery stalk can cause allergic or light-sensitivity skin reactions in some people.
 
Ginseng has been used to stimulate the adrenal glands,and thereby increase the energy level. It also may be used for reducing blood sugar in patients with diabetes mellitus. People taking NSAIDs should avoid it.  Ginseng can cause headaches, tremours, and sleepness . Avoid it if you are using medicine to prevent blood clotting .
 
Ginko Biloba is a popular treatment for dementia. Avoid use with NSAIDs. It has blood thinning properties. Avoid it in patients with epilepsy or taking seizure medication such as phenytoin (dilantin), carbumazepine (tegretol) and phenobarbital.
 
Saw palmetto has been commonly used for the enlargement of the prostate gland, it can cause upset stomach. This drug may affect the action of the sex hormone testosterone,thereby reducing sex drive.
It would be prudent to avoid concomitant use with other hormonal therapies. e.g., estrogen replacement therapy and oral contraceptives even though no drug-interaction was reported to date.
 
St. Johns Wort has about 10 uses and many have proven ineffective or of insignificant worth according to a recent study,the study report is now publically available,it has drug interactions.  It is frequently used to treat minor depression.  One recent study indicated it is equivalent to placebo in treating major depression. It may be useful in mild cases.
 
Many medicinal herbs for pain contain the salicylates from which aspirin is made. Judged on potency,willow bark may be the closest counterpart to aspir,but it is weaker then aspirin,it has far fewer side effects,including less gastric bleeding.
 
Some people with mild to moderate osteoarthritis might be able to use willow bark tea or alcohol extract to eliminate or limit reliance on aspirin,thereby minimizing some undesirable side effects.
 
The German government (where herbal products are regulated,just like drugs) recognizes willow bark extract as mildly effective for "feverish illnesses,rheumatic disorders,and headaches",and sets the minimum active dose at 60-100 mg of salicin".
 
Devil's claw root has a long folk history as a digestive aid and analegesic among southern Africa's indigenous peoples,but it was not traditionally used in antirheumatic herb. It is used quite commonly in Europe.  Devil's claw appears to be safe,based on its use in Africa, animal studies,ans on a small clinical trial The evidence of efficacy is mixed. It is important to note that harpagoside,(the characteristic compound that identifies true devil's claw extract ) has little or no anti-inflammatory effect by itself.  Choose whole root extracts,standardized for harpagoside content,to ensure that you are really getting devil's claw. 
 
Yucca the famous desert plant has gained a reputation fo its value in arthritis based on a positive result from a poorly designed clinical trial published in 1975. The clinical trial itself,was seriously flawed,so be careful with your money. Oral yucca is a very weak hemolytic,or dissolver of red blood cells,,but it is approved as a nontoxic food substance (root beer flavoring ) in the U.S. and should be safe in moderate doses.
 
The general warning is consumers beware and the right dose has a lot to do with it,overdose can have serious effects,many unknown drug-interactions,that are unknown in many herbs and  "supplements".
They are not FDA  regulated  and in the manufacturing process consumers can not be assured of the labeled quantity,quality or pureness of the product itself.

Psychoneuroimmunology is the medical terminology for the mind-body-immune system connection. Stress can impair immune function which is a major concern to RA patients.
 
Research has been done on religion and the link with a positive attitude and have proven beneficial. Negative thoughts are to be avoided. The capacity to adapt,cope and continue full function vary greatly among patients.
 
Some patients feel disabled by their symptoms,but only a few, will ever become  severely disabled. Focusing on what you are able to do rather then on what you can't do, can be helpful.Other patients find simple meditation helps to relax and better adjust the pace of their lives to the limitations imposed by arthritis.
 
Results from a national study envolving 937 mature arhtritis patients  was reported in a issue of the Archieves of Family Medicine. The study participants were asked questions about how they sought relief from arthritis and how arthritis affected them. Various disruptions to daily living were citied.
 
About one-third of the participants reported a corelation between arthritis and sleep loss. In the study.the patients who did recognize sleep loss a problem tried to find a remedy through traditional medicine,alternative medicine treatments(herbs),or self-care moreso than for any other reported disruption.
 
According to a rheumatoligist;"The insomina associated with arthritis may be due to chronic pain,arthritis related stress,or one of the many medications required for disease control. This applied to many other problems such as stomach,tiredness,eating etc.  
 
In addition many arthritics are fatigued at bed-time but not physically tired. This is due to reduced physical inactivity because of joint immobility.
 
Coping with insomina and some other problems requires complex treatment of physical reconditioning.
 
Many patients don't eat well because of the physical pain.
 
In old far eastern medicine they used to put a drop of substance on nerve pressure points and burn the substance. The  burn, interacted with--pain from the affected body part. This method was used for muscle and joint pain. Apitherapy works on the same principle--"bee-sting" to pressure points--similar to acupuncture.
 
Some patients say they have benefitted from acupuncture,others claim, they have not,and that they have to attend many sessions, and they further state that what benefit received was that of a temporary nature. Is the cost worth the benefit?
 
Despite its growing popularity,Homeopathy, the established medical community do not endorse it.Homeopathy is provided through highly individualized constitutional treatment.They concentrate on a single remedy, usually with a series of small remedies over time.
 
Treatment is typically in the form of small doses of plant,animal or mineral substance that is meant to help the immune system.It is a unregulated practise. The problem is cost and possible harmful toxicities, and no scientific data to support its validity.
 
Yoga and basic tai chi are excellent relaxation techniques with proper supervision. Chinese medicine or herbal medicine have been practised for centuries,but it is not endorsed in the western medical community because of possible serious toxicity,and drug interactions,when not properly administered.
 
Some doctors may encourage or support your use of supplemetary or complementary therapy provided it is safe,and does not interact with your regular prescribed therapy.Always consult your physician when contemplating alternative therapy. Your doctor knows your personal ,  medication, and personal physical condition.
 
University of Maryland researchers set out to determine how often rheumatoligists,the doctors who treat arthritis and related conditions,use alternative therapies--either directly themselves or indirectly by referring a patient to another practisioner.
 
The researchers sent questionnaires about 22 different alternative therapies to 2,000 physicians who were members of the American  Academy of Rheumatology. They got 924  responses back,analyzed the results and reported their findings in the current issue of the Archieves of Internal Medicine(--Barker Bausell--study co-author and associates.)
 
The alternative therapies listed in the survey were acupuncture;behavioral medicine;dietary prescription;electromagnetic application (Tens and Pens); energic healing;exercise intervention;herbal/botanical medicine; homeopathy; hypnotherapy;magnets;manipulation therapy (non-chiropractic); massage/ manuel healing;meditation;movement (yoga,qi gong);music/sound;nutraceuticals (glucasimon,s-adenosylmethionine);prayer and spirtual direction;relaxation techniques;and trigger-point therapy.
 
At least half of the doctors who responded had actually referred patients to eight of the therapies: acupuncture,behavioral medicine, biofeedback, counselling/ psychotherapy,dietary prescriptions,electromagnetic application, exercise and massage.
 
More than half had either referred or directly used nine of the 22 therapies,with counselling/psychotherapyy (85 percent) and exercise (81 percent) receiving the most response.
 
Overall,the physicians surveyed were more likely to have referred a patient than to have administered the treatment themselves,with the exception of trigger-point therapy and nutraceuticals. In these cases,51 % and 34 % of doctors,respectively,said they had used the therapy.
 
After that,the physicians were most likely to have directly been involved in exercise intervention (41 %);dietary prescription (33 %); counselling/ psychotherapy  (24 %);and electromagnetic applications (10 %).
 
The results seem to indicate an openess on the part of rheumatoligists to alternative therapies,the study concludes.
 
The study did not focus on the effectiveness of the different alternative therapies. That is an entirely different question,and one which researchers are actively investigating. Currently,there is a large trial underway to see how effective acupuncture is against osteoarthritis.
 
"That,of course,is a big,big job," Bausell says. 4/12/02.
 
"This is an important study," says Dr. John Klippel,medical director of the Arthritis Foundation. "What it reflects is an emerging trend,which has probably being going on for the last 10 years,of rheumatoligists becoming involved in complementary and alternative medical therapies."
 
"I think this has been driven by a couple of things,first and foremost by an interest by people with arthritis in using them," he adds.
 
"The second thing is that there's a growing body of evidence that [alternative medicine] can play an important role in the comprehensive treatment of someone with arthritis. Studies have appeared in journals that rheumatoligists read," he notes.
 
Kippel adds,however,that "nearly 70 % of physicians don't discuss alternative therapies with their patients because they do not feel knowledgeable enough."
 
There is no scientific evidence that diet alone will help in the fight against RA  Some people with arthritis swear by the benefits of a vegetarian diet (Most rheumatoligists and patients do not think much about diet alone,but they will say if its a healthy diet and helps you--go for it.) It may be the variety of plant foods eaten on a regular basis rather than the elimination of animal products that provides the major perks.
 
Meeting the daily quota of fruits and veggies and choosing whole grains over refined ones may be a few ways of increasing your disease fighting arsenal. Munching an apple,adding onions to your salad,sipping a cup of black or green tea,or bridging the gap between meals with a handful of peanuts will provide an assortment of phytochemicals. There are thousands of  phyto-chemicals  phyto meaning from plants--that may provide benefit.
 
Flavonoids and phytosterols are two phytochemicals that have been shown to help inflammation seen in arthritis. If you think it's simpler to fill your medicine chest with supplements,be aware that you can get too much of a good thing. As well,when you take these compounds in isolation,without the other compounds found in food,they may not have the same effect.
 
Instead,try to get a daily dozen servings of PAX foods. PAX,a term coined to include phytronutrients and antioxidants,was invented by the Boston group Oldways Exchange and Preservation Trust,the same folks that increased awareness of the Mediterranean diet.
 
They've introduced PhytoVenture,an initiative aimed at reaping the benifits of foods containing PAX. Among PAX rich options are whole grains, fruits,
vegetables,nuts,seeds and tea. Go for a variety of these foods to obtain a real mix of PAX.
 
A dozen servings of PAX foods daily may sound daunting,but in the case of most grains,fruits and vegetables,a serving is just a half cup.
 
At dinner,one cup of brown rice and one cup of broccoli provides four PAX servings.
 
At lunch,a sandwich on whole-grain bread along with sliced tomato and an orange supplies  another four.
 
Snack on fresh fruit and a couple of tablespoonfuls of nuts and you've got a couple more servings of PAX. And then there's breakfast to consider. A healthy well balanced diet is always beneficial regarless of your condition.
 
Complementary therapy is defined as therapy that is used in combination,with   conventional methods. Alternative therapy is replaced, in place of conventional treatment.

The evidence that glucosamine builds up cartilage is meagre. And even in the studies that show that it might, the amount of cartilage built up is miniscule. The studies have been done in osteoarthritis, not in rheumatoid arthritis where the damage to cartilage is much more aggressive. Any potential benefit of cartilage repair would be outweighed by the destructive inflammatory process of rheumatoid arthritis. Glucosamine might reduce some of the pain in the knee but it needs to be taken for 2-3 months to determine such a benefit.
 
The degree of cartilage loss in your knee and the prescence of rheumatoid arthritis make it very unlikely that glucosamine sulfate would restore any meaningful amount of cartilage, if any at all. 

However, glucosamine is useful for osteoarthritis, not rheumatoid arthritis. Devil's claw has not been shown to help rheumatoid arthritis and it may have some hormonal side effects such as abortion.
 
The evidence that glucosamine builds up cartilage is meagre. And even in the studies that show that it might, the amount of cartilage built up is miniscule. The studies have been done in osteoarthritis, not in rheumatoid arthritis where the damage to cartilage is much more aggressive.
 
Any potential benefit of cartilage repair would be outweighed by the destructive inflammatory process of rheumatoid arthritis. Glucosamine might reduce some of the pain in the knee but it needs to be taken for 2-3 months to determine such a benefit.
 
The degree of cartilage loss in your knee and the prescence of rheumatoid arthritis make it very unlikely that glucosamine sulfate would restore any meaningful amount of cartilage, if any at all. 
 
Some persons believe that liquid cod liver oil helps their arthritis by lubricating their joints. However there is no real evidence to support such claims. In fact, joints are lubricated by mucus like hyaluronic acid not by oils such as the fatty oils in cod liver oil.
 
Cod liver oil contains vitamins A and D and omega-3 polyunsaturated fatty acids.  Vitamins A and D are not known to help arthritis but vitamin D is important for normal bone growth and maintenance. There is a danger in taking too much cod liver oil and developing vitamin A and D toxicity.
 
 The omega-3 fatty acids include EPA (eicosapentenoic acid) and DHA (docosahexanoic acid) which have been shown to have a mild anti-inflammatory effect on arthritic joints. However, these fatty acids can be purchased in a pure form with an exact dosage and  without the danger of developing vitamin A and D toxicity.
 

Complementary Therapy:
 
Eicosopentaneoic acid (EPA) and gammalinolenic acid (GLA) have been shown experimentally to be anti-inflammatory and to blunt immune responses.
 
Fish oils,including cod liver oil,contains EPA.
 
Plant oils specifically oils from evening primrose and borage,contain GLA.
 
Theoritically,blackcurrent seed oil is even better,because it contains both GLA and a chemical which is converted to EPA
 
Studies with these oils have shown that they definetly reduce the "tenderness and pain" index in rheumatoid arthritis,and may affect the extent of the swelling as well.
 
 But studies have only looked at high doses. It remains to be seen whether lower doses, (safety-factor),which would be much safer and easier to take,will be as good.
 
Seaton is an extract of the New Zealand green-lipped mussel. It appears to have some anti-inflammatory effect in the lab and rats,but well designed studies haven;t turned up any evidence of effectiveness in rheumatoid arthritis or osteoarthritis. It is expensive.
 
In the last few years,three dietary supplements-glucosamine (with or without chondroitin), SAM-e and MSM-have been popular. Glucosamine- it seems to help patients with osteoarthritis pain,but has never been shown to be effective in inflammatory arthritis like RA.
 
SAM-e ("sammy" or S-adenosylmethionine) is an antidepressant and early studies support its claim as a pain reliever. It has also been recommended as an anti-arthritis-but without proof,at least so far. At $1.00 (Canadian) per 100 mg caplet (recommended dosage 4 to 16 a day),it is expensive
 
MSM,which is a breakdown product of dimethylsulfoxide (DMSO),is being promoted by a great deal of advertising and word-of-mouth enthusiasm as a arthritis cure. There is no convincing studies,but I have seen some written by pharmicist-their advice stay away from it .
 
A couple years ago there was a write up about a Chinese herb called thunder god vine,in a prestigious medical journal and it listed warning signs about the herb. I forgot the contents about the article,but noted that I would stay away from it. Probably the side effects of the herb was valid. Recent studies have been done.
 
Triptolide-its active ingredient have been isolated. It has now ben tested in the lab and shown to keep immune cells from turning on the inflammation chain reaction. It is also believed have anti-cancer actions. The trip from lab to pharmacy has been a troubled and long journey. 
 
Zinc,selenium,copper and vitamin B and C have been investigated Addition of these does not affect arthritis.
 
A small study was done on a diet that eliminated red meat,dairy products,alcohol,preservatives,fruits and spices. A slightly different study showed that 17 patients put on a long-term vegetarian diet improved and were able to maintain their improvement fo at least a year.
 
Nutritionists examining this study have criticized it for two reasons: the numbers were too small,and the diet itself had nutritional deficiencies that could lead to difficulty over the long run.
 
There is no blanke prescription. A small nunber of individuals-probably a few- have food allergies that cause symptoms. In other instances,a vegetarian-type diet may modestly improve the signs and symptoms of inflammation. But for moderate-severe RA ? We haven't heard the last word on dietary manipulation.
 
There have ben clear-cut instances where arthritis sysmptoms in patients diagnosed as having rheumatoid arthritis have come and gone in response to the addition and addition of specific foods give in a "double-blind: fashion. the foods varied by patient,and included corn,wheat,nitrate shrimp,and milk.
 
Most of the patients appeared to be rheumatoid fator (RF) negative. but estimates of the number of RA patients whose symptoms are affected by food are well under 5 %. The scientists argue that there is no scientific evidence to support diet or food have on effect on rheumatoid arthritis,as of today.
 
The National Institue of Health found that acupuncture may be a reasonable plan option for Osteoarthritis. More recently,the American College of Rheumatology reported that acupuncture works no better than a placebo.
 
Acupuncture may be worth a try,particularly if you're attempting to deal with longstanding,diabling,non inflammatory pain. But don't give up on conventional medicine. It seems to work best when it's co-ordinated with a variety of other approaches-physiotherapy,fitness and muscle strengthening,behavioral modification. There are various schools of acupuncture.
 
We need larger studies to find out what types of arthritis benifit from the procedure .Acupuncture needle stimulation in experimental animals causes release of natural painkillers (endorphins).
 
According to folk wisdom,when you wear copper bracelets small amounts of copper pass through your skin and neutralize free radical,which are toxic molecules that damage cells. Wearing copper jewelry is probably harmless,but most doctors find no scientific basis on which to recommend them.
 
Guided imagery and hypnosis can help you relax by creating a vivid and plesant mental picture. In you're mind's eye,e.g., You might see yourself lying on an ocean beach on a summer day listening to slow,gentle waves lapping against the shore.
 
Hypnosis is another controversial subject. Some experts see no value,while others claim it does
 
A related option may be biofeedback. During a biofeedback session,various machines monitor you and give feedback on certain body functions--heart rate,breathing patterns,body temperature and more. When you enter a relaxed state,some of these functions change. By monitoring such changes,you might learn how to produce them voluntarily and better cope with pain.
 
Meditation help you enter a deep,restful state that reduces your body's stress response. Meditating regularly can relax your breathing,slow your brain waves,and heart rate. Medical professionals acknowledge that  therupeutic massage (when done properly) can help some patients and promote relaxation.
 
 More study is needed to determine whether plant oils derived from plant extracts and resin can help various illness when massaged into your skin or inhaled (generally).
 
Joint manipulation is practised by chiropractors and osteopaths. They claim that the treatment can relax the tissue surrounding the joints,improve circulation and make joints more mobile. However, it's unclear whether joint manipulation or realignment of the spine helps relieve joint pain caused by OA 
 
If you have RA avoid neck manipulations. The chiropractors association endorses neck manipulations as safe,but some patients have been crippled. There are some outstanding law-suits pending,with regard to this procedure. In Canada one chiropractor settled a  $1,000,000 law-suit out of court despite association backing.
 
Researchers are starting to look at magnets as a possible therapy for pain associated with arthritis. Some studies show benefits. Some researchers believe in appropiate use of magnet therapy. Actually,it could lead to health problems. You should not bring a magnet within 6 inches of a pacemaker.
 
According to some alternative practisioners,bee venom has enzymes that relieve the symptoms of RA. Others think that bee venom stimulates your body to produce more steriods,which may help symptoms. 10 to 15 % of the population has mild to fatal allergic reactions to insect venom,so this treatment is risky to some individuals. 
 
Snake venom is  toxic to some people,so arthritis experts warn against this treatment until more research has been done. The FDA has not approved any arthritis medication derived from snake venom.
 
Unfortunately,there have been few scientific experiments with fish oils in patients with RA that have shown favourable results,and consequently a practical,and safe dose are still unknown in this dietary therapy.
 
 In most of the studies using fish oils,benefits are not usually observed until at least 12 weeks of continuous use and appear to increase with extended treatment time.
 
Tests which favour fish oil indicate the inflammation improvement is moderate,
equal to what NSAIDs give.
 
It is important to note that fish oil supplement may interfere with blood clotting and increase the risk for stroke especilly when consumed in conjunction with aspirin or other NSAIDs. Taking fish oils has also been linked to change in bowel habits such as diarrhea and may cause upset stomach.
 
Until more is known about safe doseage for omega-3 fatty acids, supplemen -tation  in the form of gelatin capsules is not advised by some medical professionals. Rather increased consumption of fish rich in omega 3 fatty acids such as salmon,herring and mackerel may be safer.
 
Whether omega-3 fatty acids should be included as standard  therapy for RA remains controversial.--( Baron/John Hopkins/) .
 
A consumer testing laboratory did some testing on supplementary tablets of fish oils containing omega-3 fatty acids by different manufacturers and they concluded that the quantity actually advertised,and what was actually found  differed by different producers.  Other researchers said the high dose needed ( supplement-capsules) for efficacy is of concern.
 
Professor Bruce Caterson,Cardiff,Wales U.K. reported what thousands of people with arthritis have said for years,and some scientists said was "old-wives-tales"--that cod liver oil,really is effective in controlling joint pain in osteoarthritis. According to Caterson,the omega-3 fatty acids in cod liver oil work by switching off the aggrecan and collagan--degrading enzymes that breakdown the cartilage.
 
"A case of old-wives-tales and science coincide",says Caterson. He hopes to publish his findings in Arthritis and Rheumatism publication. Caterson's intension is for those patients that can not take NSAIDs due to the side effects. (News release did not mention dose).
 
Some research studies suggest that vitamin C may help people with OA. Other studies suggest worsening of OA.  According to some investigators  osteoarthritis of the knee may be partially  associated with low levels of Vitamin D in the diet.
 
Taking too much Vitamin A may worsen osteoarthritis as reported by some  other studies.
 
Elimination diets require you to stop eating certain foods. One such diet forbids night-shades vegetables,such as potatoes,eggplants,bell peppers and tomatoes--you can go to far. According to the Arthritis Foundation,food sensitivities may play a role in arthritis.
 
However,scientist disagree on how common the problem is and what food,if any,to avoid Before you alter diet ask a dietician. You can always eliminate one food product at a time and see whether symptoms can be helped.
 
Does homeopathy work ? Again we come to controlled studies,and again the data just isn't there. There has been only one small acceptable study in RA. In contrast to a number of other reports that showed no benifit,it demonstrated a reduction in pain in patients recieving homeopathic treatment
 
This study has ben criticized on the grounds that patients weren't assigned in a random fashion to one group or the other,and so it does not meet strict study criteria.
 
In most Western countries,including Canada and the U.S.,herbal remedies are classified as foods and don't have to pass the more strigent regulations applied to drugs. Quality control appears to be a big problem.
 
Analysis has shown some preparations to be adulterated with other drugs,and with heavy metals. This is particularly true of products for which there's a huge market-and many unscrupulous individuals wishing to share it.
 
 

SOME GUIDELINES FOR USING HERBAL MEDICINES.

1. Approach any herbal medicine as you would a prescription drug or over-the-counter (OTC) drug. Herbals can have adverse effects, drug interactions, contraindications (conditions when they should not be used), and all the other problems that go along with the kinds of medications you are used to. Some are widely recognized to be dangerous, but are still allowed to remain on the market.

In fact, you should even be more cautious when using an herbal than a prescription or over-the-counter (OTC) drug for many reasons.

Herbals are virtually unregulated. You are not protected by the same government controls exercised over prescription and OTC drugs. This means there is no assurance that what it says on the label is in the bottle. Also, because of lack of regulatory controls, herbals are marketed in a way that may make them look like what they aren't and they are held out with claims they can't fulfill. Their labels may not disclose their adverse effects and everything else you would expect on drug labels.

Lack of knowledge about herbals. Only now are medical, pharmacy and other professional schools gearing up to give their students the kind of intense instructions they should have on the subject.

Some herbal medicines are unsafe, ineffective, and potential killers.

When initiating a course of herbal medicine treatment, start with one herb only so you can clearly identify its adverse effects and benefits. Otherwise, if you start with a bunch at one time, it may not be clear which one is causing problems or which one is working. The same process makes sense in initiating drug therapy.

2. People with special conditions should proceed with special caution, and get the advice of a doctor, pharmacist or other qualified professional before taking an herbal medicine.

People with special conditions include but are not limited to

Pregnant and nursing mothers

Anyone with impaired immune system

Anyone with impaired liver or kidney function

Anyone with chronic disease such as diabetes or heart disease,

Young children (especially infants)

Senior citizens

Anyone taking prescription medicines

The Mayo Clinic Family Health Book (2nd edition) says flat-out, "Don't give herbal supplements to children."

If in doubt, anyone, in perfect health or not, should get the advice of their doctor.

In some cases, it may be more convenient to ask your pharmacist, who may be able to advise you on the herbal medicine and whether you should consult your doctor before taking it. You should use your pharmacist as an automatic check on what your doctor recommends in terms of drugs, herbal medicines, food supplements and the like.

3. When getting advice from your doctor, pharmacist or other qualified professional on herbal medicines or on other matters, you should tell them about all the herbal medicines you're taking, along with other nutritional supplements, vitamins, minerals, prescription and over-the-counter drugs. In other words, what herbal medicines you're taking should be part of your medical history. A competent doctor should ask you about all of the drugs, nutritional supplements, herbal medicines and anything else you're taking as a part of your medical history and before prescribing any treatment.

When seeking advice from a pharmacist or any other professional, you should also be sure your medical history is fully communicated.

4. When getting advice from your doctor, pharmacist, or other health care professional, make an allowance for the fact that the major focus on herbal medicines is so new, your advisor may simply not be informed on the subject. Recently, the American Pharmaceutical Association found only one-third of pharmacists felt comfortable in advising patients about herbal medicines. The percentage of doctors, in my view, is likely to be just as low or probably lower. Dr. Dan Hussar, a leading authority on pharmacy practice, says that pharmacists are in a unique position to assume a major role in counseling on herbal medicines and will become the authorities on the subject. Other professional groups can also be expected to develop expertise in this area.

5. Check it out yourself by going to the growing number of useful books and web sites on the subject. There are now many sources available for checking out herbal medicines on your own. We've already mentioned The PDR for Herbal Medicines. Other good sources are the Review of Natural Products (formerly called The Lawrence Review of Natural Products), published by the same company that puts out the widely used and highly regarded Facts and Comparisons on drugs; Dr. Varro Tyler's books including The Honest Herbal, available in paperback and hardback, and Herbs of Choice: The Therapeutic Use of Phytomedicinals; The Professional's Handbook of Complementary and Alternative Medicines published by the Springhouse Corporation; The American Pharmaceutical Association Practical Guide to Natural Medicines; Dr. James A. Duke's The Green Pharmacy; and Jean Carper's books, including Miracle Cures and Food Your Miracle Medicine.

There is also a web site maintained by the National Institutes of Health that includes a data base of studies on herbal medicines at http://odp.od.nih.gov/ods/. Other valuable sites, among many others, are those of the American Botanical Council, www.herbalgram.org., and the site of the American Herbal Products Association, www.ahpa.org. A good continuing source of information on herbal medicines is Consumer Reports on Health, the newsletter published by Consumer Reports.

6. Don't fall for the idea that herbal medicines are perfectly safe because they are natural. There are huge catalogs of natural substances that can be deadly ranging from arsenic and hemlock to opium (from the poppy). And what could be more natural than the rays of the sun, which can cause melanoma and other skin cancers? Of course, as the PDR for Herbal Medicines notes, "Some -- such as ginkgo, valerian, and saw palmetto -- seem genuinely useful, while others -- such as ephedra, tansy, and nightshade -- can actually be dangerous." The Mayo Clinic Family Health Book (2nd edition) reports that Ma huang may cause a dangerous increase in blood pressure, and germanium's long-term use may cause kidney damage and death. Yohimbe may cause tremors, anxiety, high blood pressure and rapid heart beat; and chaparral may cause liver disease. Mayo also notes that toxic chemicals in comfrey, borage and coltsfoot may cause liver disease.

7. Avoid the widespread fallacy that if some is good, more is better. This is dangerous. Whenever you start taking extraordinarily large doses of an herbal you increase the chances of adverse effects and other problem. The same is true for medicines, vitamins, minerals and all other dietary supplements.

8. If you do decide to use a herbal medicine, ask your doctor and pharmacist for recommendations on the brand to buy, and check out the brand and source. Many suggest that you increase your chances of getting a standard and reliable product if you buy an herbal from one of the major drug companies that are now moving into the market. Other suggestions of quality include products that carry the seal of the National Formulary (NF), which indicates the product meets the specified guidelines of the U.S. Pharmacopoeia (USP), a respected standard-setting organization. Such products whose manufacturer asserts they meet NF standards will be coming onto the market by the end of 1999. However, the USP is still in the process of setting standards for herbals and is many years from completing the job.

Still another indication of quality is the fact that the product is also sold in Germany, where higher regulatory standards are set for herbs. In Germany, an agency of the government — called the Commission E — regulates herbals in a fashion similar to the FDA's regulation of drugs in the U.S. Commission E has published 300 monographs on herbal medicines and has allowed about 700 herbals on the market. Some 80 percent of German doctors use herbals. Dr. Ara DerMarderosian, a nationally known expert on herbals, says if you want more information, you can write or call manufacturers and they should provide details about their product and the testing and quality control standards. Many manufacturers have toll-free 800 numbers making it easy to contact them. In the case of bulk herbs, one expert, June E. Riedlinger, offers this advice: "If the patient is buying bulk herbs, it is important to select a product that is labeled with the identity of the plant and that still has its color, is free of evidence of bacteria or fungus, and carries data indicating when the plant was collected."

9. Buy any herbal from a reliable store so you increase your chances of getting a fresh product and a quality product. Check any expiration dates or other freshness information on the label. Varro E. Tyler says, "The labeling of herbal products should show the scientific name of the botanical, the name and address of the actual manufacturer, a batch or lot number, the date of manufacture, and the expiration date." You should also check for dosage information (it may indicate dosage information under a section entitled "recommendation" or "suggested use"). Also check for storage information (which may say store in a cool, dry and dark place which is inaccessible to children; some containers say store in a dry place at controlled room temperature. Avoid heat above 80 degrees Fahrenheit). Some containers come with child resistant caps and safety seals.

10. While using an herbal medicine be alert for any possible adverse effects and report them to your doctor immediately. You should be aware that any new symptoms may relate to the herbal medicine. Some recommend you keep a journal and record each day the effect you experience in using the product. Dr. Varro E. Tyler has advised pharmacists to "advise patients to cease taking a natural product (herbal medicine) immediately if adverse effects (e.g., allergy, stomach upset, skin rash, headache) occur."

11. You should also report your experience with adverse effects to the Food and Drug Administration at 800-332-1088 (more easily remembered as 800-FDA-1088) or the U.S. Pharmacopeia at 800-4USP-PRN (the PRN stands for Practice Reporting Network). That number is more easily dialed at 800-487-7776. Those two organizations share information.

12. Don't put off needed medical treatment with the hope that some self-prescribed herbal medicine will solve your problem. You can endanger your health and life by delaying treatment of many conditions that may progress to become much more dangerous or even fatal if not promptly treated. Don't try to use herbal medicines in place of needed medical advice.

13. Approach any recommended herbal medicine or any other medical recommendation for that matter, with a skeptical and inquiring mind. Ask questions. Get answers. Check out recommendations. And needless to say, don't rely on medical advice from a clerk or owner of a health food store. Remember that herbals are neither panaceas nor therapeutic pariahs. They range from dangerous to valuable, and some are used by the most highly qualified physicians. As in much of life, two key Latin words, which make sense in all languages and in all contexts, are worth observing — caveat emptor. Buyer and user beware.

The theory behind "free radicals" : The unstable oxygen compounds called "free radicals" are essential to life and to normal immune response,but they play a destructive role in chronic rheumatical inflammation.
 
In what has become a vicious cycle,free radicals stimulate production of inflammatory mediators which tend to stimulate production of more free radicals,and so on.
 
Even after immune system cells release anti-inflammatory mediators,free oxygen radicals can keep the flame burning for a time. In RA patients,whose blood levels of antioxidant enzymes (glutathione, superoxide, dismutase, catalase)   are abnormally low,free radicals are left relatively unchecked to do damage.
 
The theory belief is that carefully selected herbs may supplement conventional medicine and are helpful precisely,because they possess the antioxidant power to neutralize free oxygen radicals.
 
New research suggest that antioxidant compounds that act on cytokines-cutting off the inflammatory command at the source-may be even more important than the antitoxidants that act to scavenge the free radicals that local immune cells release at the behest of cytokine messengers.
 
These include carotenoids,essential fatty acids,soy isoflavones,vitamin E, branched-chain amino acids.curxumin,lipoic acid,and phenolic flavones from such foods as green tea,rosemary,and grape seed extract (OPC)
 
Which makes sense as long as conventional therapy is followed and complementary therapy introduced,intelligently,or to those patients unable to follow conventional,time-tested and clinically-tested therapies.
 
 In other words,use complementary therapy to supplement conventional therapy without ,total replacement of conventional therapy.

Curcumin is the main active constituent in turmeric,an Indian herb with an ancient history of medicinal use against inflammation. Known to India's Ayurvedic physicians as rajani,turmeric is most familiar to Westerners as the bright yellow element in curry powder. This spice is a close cousin to ginger. Curcumin is a name for the antioxidant pigment in turmeric,called curcuminoids (natural NSAIDs). Whole turmic contains only about 5 % curcumin. making its anti-inflammatory action rather weak. You can now purchase standardized dietary supplements of turmeric that contains 95 % or more curcumin.
 
There is a family of antioxidant plant compounds called oligomeric proanthocyanidins (OPCs) or pycnogenols.  Supplemental OPCs have been used in Europe since 1950 to treat weak blood capillaries,postsurgical edema (swelling),cirrhosis,varicose veins,and diabetic retinopathy. The early research into OPCs as a treatment for capillary fragility hinted at their potential value in connective tissue disorders,but this limited focus understates their therapeutic promise and until recently,has distracted scientists from looking into broader uses for OPCs
 
Some researchers call OPCs "vitamin C2",because they restore tha antitoxidant function of vitamin C molecules worn out by free radicals scavenging activities. Vitamin C is critical to immune functions and the health of connective tissues,making it and OPC valuable to people suffering from arthritis,cardiovascular disease,and other conditions involving degradation of connective tissue (e.g.,joints,artery walls) As yet,there are no clinical trials to support the theory,but work done in the laboratory,looks very promising.--Grape skin extract,pine bark extract,pycnogenol -anti-inflammatory-antioxidant-collagen protective). We should hear more about this in the future.

An approach similar to biofeedbck was developed by Dr. Wells in the wake of the gate-control theory,called transcutaneous electrical nerve stimulation,or Tens, (minor pain). Electrodes taped to the skin near a painful area are wired to a electrical stimulator,which produces a series of electrical pulse that "closes the gate" on the nerve cells that transmit pain signals to the brain. You adjust the strength of the pulses until you feel a slight tingling.
 
Massage is widely used for pain relief,not least because anyone can perform it on himself or others,but it's results are open to question. At best,massage (professional massage) may relieve muscle ache or tension,and it's results are relatively short-lived. There is no question that a soothing stroking action ,on a painful area,done by yourself has a soothing effect and it's cheap unlike the former.
 
Heat is another common treatment method (though it shouldn't be used on already inflamed joints}. From hot springs and spas to Finnish saunas,relief is most likely due to general relaxation a sense of well-being . Exercising in a heated pool will enable patients to do exercise that may not be done on dry land.. Heating pads is dry heat-what a muscle in spasm really needs is moist heat,as in a water bottle.
 
Cold,not heaat is the recommended treatment for inflamed joints Ice packs,even a bag of frozen objects wrapped in a towel can provide temporary relief,but then again some people can not stand cold packs.
 
Diathermy uses small paddles taped to the skin to direct electromagnetic radiation (as against the pressure waves of ultrasound-another method) to heat a part of the body or limb from the middle outward.
 
If you have inflammatory arthritis,splints and other custom orthotics protect fragile joints from injury and keep them properlu aligned,thus reducing pain.
 
Counterirritants,which include liniments,vaocoolant spray and poultices,work by pitting one pain against another,inducing the body to lower it's sensitivity . Applied to a painful joint,they produce a trmporary local reaction that may cause skin irritation,mild swelling,or a temperchange change and lessening  of pain. Most countrtirritants "distract" the brain from recognizing the signal from the pain source,a gate-theory effect.
 
A more effective compound would interrupt the flow of the neurons sending the signals in the first place. That's what a substance P "antagonist" like capsaicin does Prescription salves are available in such brand names as Zostrix,Capzasin-P and Capsin etc. Be careful not to get it into your eyes,via through your hands,while rubbing it in.
 
Capsaican,the hot chemical in chilies,is a slow-acting but effective topical (external) treatment for pain. For unknown reasons,it appears that capsaicin has more effect on the pain of osteoarthritis than on rheumatoid arthritis pain.
 
Instead of hypnosis psychotheraphy may be more appropriate in providing people with "assistance in plannining their lives and thinking differently about things". Where hypnosis does show encouraging results is when it's combined with other treatments. Hypnosis,aid, in RA remains questionable.
 
Try to avoid thinking about pain,if you can,although it is hard,not to.

Improvise! Just because you have arthritis doesn't mean that every piece of equiptment is going to work for you. No one's joint function is exactly the same as anyone else's,an a tool or device designed for someone with mild OA may not be ideal for someone with severe RA-for that matter,it may not be equally suitable for two people with mild OA. Make sure the device you're thinking of buying works for you before you put down any money. Otherwise you're liable to end up with a closetful of doorstops and paperweights.
 
By all means,consult the professionals-from the supplier of aids and devices to the members of your health care team. Many of the best solutions to disability impediments are engineered by patients.
 
How ? Learn to be flexible. Discover ways to alter your lifestyle to meet the demands of the disease,and exercise as much ingenuity as you can muster to deal with the minutes of life. From the time you wake in the morning ("How do I lift my stiff,aching body out of bed ?" to the time you go to bed at night ("I can't reach my toes-how am I going to get my shoes and socks off ?"),you may need a whole new bag og tricks to ease your burden-and your mind.
 
There are lots of ways to adapt your environment. Start by making your activity centres,be it kitchen or workplace,as convenient as possible. Organize materials so you can reach them with a minimum of twisting and stretching,preferably from a seated position.
 
Beyond the lightweight and ergonomically designed housewares available-knives,scissors and clamps,touch-activated lamps,oversize button on the phone,and grab bars and non-slip mats for the bathroom-are all sorts of economical tricks. You don't have to buy expensive cutlery-build up the handle of your paring knife with friction tape, replace round doorknobs and taps with lever-type handles,or build them up with rubber grips or elastic.
 
Clothing is infinetely adaptable. Try Velco fasteners in place of buttons, and equipt zippers with pull rings for easier use. Loose clothing is easier to get in and out of. Slip-on shoes are preferable to shoes with laces,and shoehorns are available with extra-long handles,so you don't have to bend over. In winter,a long coat offers more protection for sensitive joints from the frigid air,and ir it has large pockets,you may be able to dispense with a hand bag or shoulder bag-back-pack is even better,but some may not prefer the looks. For women,front-closing bras and wrap-around skirts are much easier to put on. Clthing in easy-to-care fabrics need little or no ironing or hand washing.
 
Even your car can be adapted for ease of use: You can have a swivel seat installed,which makes getting in and out a snap,there are special "one-handed " seatbelts available,and you can avoid some twisting and turning by mounting a multipart rearview mirror. For stiffened hands and fingers,get a built-up handle for your ignition key and a padded cover for the steering wheel.
 
Arthritis imposes a lot of barriers on everyday life,but don't let it stop you. Staying active as you can-mentally and physically-is the way to approach the disease.

Transcutaneous electrical nerve stimulation (TENS) is a drug-free method of pain relief that has been used to treat a wide variety of muscle and joint problems, as well as many other painful conditions. TENS uses electrical impulses to stimulate the nerve endings at or near the site of pain, diminishing the pain and replacing it with a tingling or massagelike sensation.

TENS can be used in a health-care setting, but most often the patient uses it at home. Researchers still are not certain exactly how TENS works. The two explanations suggested most often are that electrical stimulation of the nerves blocks the pain sensation and that TENS triggers the release of the body's natural painkillers, called endorphins.

A TENS device consists of an adjustable power unit and electrodes that attach to the power unit via wires.

  • The typical power unit is small — about the size of a beeper or a cell phone. Controls allow the patient to adjust the intensity of the stimulation. Some units also adjust for either high-frequency or low-frequency stimulation. Frequency is a measure of the number of electromagnetic waves in a given time period.

  • Electrodes come in a variety of shapes. They usually are self-adhesive and made of cloth or foam. A gel is applied under the electrode to improve the flow of current.

Before beginning treatment, the patient must put the electrodes in place — usually on top of or next to the painful area. Patients can experiment with different locations for the electrodes to see what provides the best pain relief. In some cases, it may be more effective to position the electrodes on top of a related nerve or a site that is considered to be a trigger point or acupuncture point for the painful area.

Electrical stimulation can be used in the following ways:

  • Conventional TENS — This is the most typical type of treatment. It uses a high stimulation frequency, but the intensity of the electrical stimulus is low. Patients usually leave the electrodes on for long periods of time, turning them on and off at intervals. A typical treatment might last 30 minutes, but the length can vary depending on patient needs. Pain often is relieved only while the treatment is under way, but the relief may last longer.

  • Acupuncturelike TENS — In this case, the stimulation frequency is low, but the electrical impulse is quite intense. Some patients find this more effective or longer lasting than conventional TENS. Other patients find acupuncturelike TENS too uncomfortable.

  • Percutaneous electrical nerve stimulation — PENS, as it is known, is a combination of acupuncture and electrical stimulation. Instead of electrodes, PENS uses needles to penetrate the skin and deliver the electrical stimulatio

TENS has been used in patients with muscular pain, osteoarthritis, rheumatoid arthritis, sciatica, pain after surgery and other conditions.

Studies have shown varying results as to how well TENS works, what types of pain it can best relieve and how long the relief lasts. Many people have found TENS helpful, however, and many doctors recommend it as part of an overall pain-management progr

  • Advantages

    • TENS does not involve the use of drugs. For patients who find it helpful, TENS can reduce drug use for pain relief and thus reduce the side effects of drugs.

    • Some patients also like TENS because they are in control and can adjust the length and intensity of treatment.


  • Disadvantages

    • TENS can cause skin irritation. This often can be avoided by changing the type of gel or electrode used.

    • TENS is not always effective.

    • Electrical stimulation should not be used on the front of the neck. This can be dangerous.

    • People who wear pacemakers should ask their doctors about whether TENS is safe for them. TENS can interfere with the operation of some types of pacemakers.

    • It is not clear whether TENS is safe for pregnant women.


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